Recent Advances in Treatment of H. pylori Peptic Ulcer Disease

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Parietal Cells of stomach lining
Mucus
Neutralized Acid
Drug

Recent Advances in Treatment of H. pylori Peptic Ulcer Disease

Neil Fam, BSc, MSc

Helicobacter pylori was first isolated from human gastric mucosa in 1983. Since that time, recognition of its role as a major etiological agent in the pathogenesis of peptic ulcer disease has revolutionized the approach to diagnosis and treatment of this common condition. Approximately 90% of patients with duodenal ulcers and 80% with gastric ulcers not associated with non-steroidal anti-inflammatory drugs (NSAIDs) are infected with H. pylori.